Di-n-butyltin(IV) Complexes Derived from Heterocyclic β-diketones and N-Phthaloyl Amino Acids: Preparation, Biological Evaluation, Structural Elucidation Based upon Spectral [IR, NMR (1H, 13C, 19F and 119Sn)] Studies

摘要

Stable, six coordinated Bu2SnLA type complexes have been prepared [where LH =RCOC:C(OH)N(C6 H5)N:CCH3; R = -4-F-C6H4-(L1H), R = -4-Cl-C6H4-(L2H), R= -4-Br-C6H4-(L3H), R=-CF3(L4H) and AH = C(O)C6 H4 C(O)NCHR'COOH; R'= -H(A1H), -CH3(A2H), -CH(CH3)2(A3H)] by the interaction of 1:1:1 molar ratios of di-n-butyltin(IV) dichloride with corresponding organic moieties inrefluxing benzene using two moles of Et3N as a base. In these complexes LH and AH behave as bidentateand coordination is taking place through oxygen, this is inferred from IR and 13C NMR studies. Thesecomplexes possess tin atoms in skew trapezoidal bipyramidal geometry with the C-Sn-C angles ranging from149.88° to 156.84°. Some of these complexes with their corresponding organic moieties (LH, AH) weretested for their antimicrobial activities.